Gene ID | Entry | Entry Name | Protein Name | Type | Information | 22670 | Q99PN3 | TRI26_MOUSE | Tripartite motif-containing protein 26 (EC 2.3.2.27) (Zinc finger protein 173) | DISRUPTION PHENOTYPE | TRIM26 attenuatess the production of proinflammatory cytokines in response to TLR ligands, TNF-alpha, and IL-1beta stimulation. In addition, the challenge of TRIM26-deletion mice with LPS results in inflammatory responses that are less lethal than those in wild-type mice. {ECO:0000269|PubMed:34017102}. |
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