Gene ID | Entry | Entry Name | Protein Name | Type | Information | 231600 | Q810L3 | CHFR_MOUSE | E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING-type E3 ubiquitin transferase CHFR) | DISRUPTION PHENOTYPE | Mice are viable and have no obvious developmental defects. They are however cancer-prone and develop spontaneous tumors. They also display increased skin tumor incidence after treatment with dimethylbenz(a)anthracene. {ECO:0000269|PubMed:15793587}. |
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