Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:232816
  • Symbol:Zfp628
  • Description:zinc finger protein 628
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
232816 Q8CJ78 ZN628_MOUSE Zinc finger protein 628 (Zinc finger protein expressed in embryonal cells and certain adult organs) DISRUPTION PHENOTYPE Viable, with no gross morphological or behavioral phenotypes. Males are infertile with complete absence of mature sperm. Spermiogenesis arrests at the round spermatid stage, accompanied by extensive apoptosis within the seminiferous tubules. Expression of spermiogenesis-associated genes TNP1, TNP2, PRM1 and PRM2 in testis is significantly reduced. {ECO:0000269|PubMed:31932482}.