Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:232944
  • Symbol:Mark4
  • Description:MAP/microtubule affinity regulating kinase 4
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Gene ID Entry Entry Name Protein Name Type Information
232944 Q8CIP4 MARK4_MOUSE MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) DISRUPTION PHENOTYPE Hyperphagia, hyperactivity and hypermetabolism leading to protection from diet-induced obesity, and improved glucose homeostasis due to up-regulation of AMPK kinase activity. {ECO:0000269|PubMed:22992738}.