Gene ID | Entry | Entry Name | Protein Name | Type | Information | 23797 | Q9WUA6 | AKT3_MOUSE | RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) | DISRUPTION PHENOTYPE | Results in the cytoplasmic accumulation of the master regulator of mitochondrial biogenesis, Ppargc1a, and a reduction in known Ppargc1a target genes, which leads to an abnormal mitochondrial phenotype in the brain tissue. {ECO:0000269|PubMed:18524868}. |
---|