Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:23859
  • Symbol:Dlg2
  • Description:discs large MAGUK scaffold protein 2
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Gene ID Entry Entry Name Protein Name Type Information
23859 Q91XM9 DLG2_MOUSE Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93) DISRUPTION PHENOTYPE Mice do not respond to persistent pain. Postsynaptic surface expression of NMDA receptors and NMDA receptor-mediated synaptic function are reduced in dorsal horn neurons of the spinal chord. {ECO:0000269|PubMed:12890763}.