Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:23876
  • Symbol:Fbln5
  • Description:fibulin 5
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Gene ID Entry Entry Name Protein Name Type Information
23876 Q9WVH9 FBLN5_MOUSE Fibulin-5 (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) DISRUPTION PHENOTYPE Mice survive to adulthood, but have a tortuous aorta with loss of compliance, severe emphisema and loose skin. They exhibit a severely disorganized elastic fiber system throughout the body. {ECO:0000269|PubMed:11805835}.