| Gene ID | Entry | Entry Name | Protein Name | Type | Information | 24108 | P63072 | UBD_MOUSE | Ubiquitin D (Diubiquitin) (Ubiquitin-like protein FAT10) | DISRUPTION PHENOTYPE | Spontaneous sporadic apoptotic death. Higher sensitivity toward endotoxin challenge. Abrogated TNF-alpha-induced NF-kappa-B activation and reduced induction of NF-kappa-B-regulated genes. Impaired TNF-alpha-induced I-kappa-B-alpha degradation and nuclear translocation of p65 in RTECs. Reduced expression of LMP2. {ECO:0000269|PubMed:16782901, ECO:0000269|PubMed:19959714}. |
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