Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:244281
  • Symbol:Myo16
  • Description:myosin XVI
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Gene ID Entry Entry Name Protein Name Type Information
244281 Q5DU14 MYO16_MOUSE Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16) DISRUPTION PHENOTYPE Triple knockout mice NYAP1/NYAP2/MYO16 are fertile and appear healthy. However, compared to wild-type mice they show a clear reduction in brain size, exhibiting a reduction in the size of the cortex and striatum, but not the olfactory bulb or corpus callosum. The total neurite length of neurons in these mice is also significantly shorter. {ECO:0000269|PubMed:21946561}.