Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:26385
  • Symbol:Grk6
  • Description:G protein-coupled receptor kinase 6
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Gene ID Entry Entry Name Protein Name Type Information
26385 O70293 GRK6_MOUSE G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6) DISRUPTION PHENOTYPE Deficient mice show significant altered central dopamine receptors regulation, deficient lymphocyte chemotaxis and increased acute inflammation and neutrophil chemotaxis. {ECO:0000269|PubMed:12032308, ECO:0000269|PubMed:12718862, ECO:0000269|PubMed:14634128}.