Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:30044
  • Symbol:Opn4
  • Description:opsin 4 (melanopsin)
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Gene ID Entry Entry Name Protein Name Type Information
30044 Q9QXZ9 OPN4_MOUSE Melanopsin (Opsin-4) DISRUPTION PHENOTYPE Mice fail to show a pupillar reflex, photoentrainment of the circadian clock and other non-image forming responses to light (PubMed:12808468). Newborn mice show normal hyaloid vessel numbers and normal vessel cellularity, however vessel numbers are increased by P8 (PubMed:30936473). In Opn4 and Pde6b double knockout mice optokinetic visual tracking response is abolished (PubMed:26392540). {ECO:0000269|PubMed:12808468, ECO:0000269|PubMed:26392540, ECO:0000269|PubMed:30936473}.