| 329064 | A2A259 | PK2L1_MOUSE | Polycystin-2-like protein 1 (Polycystin-2L1) (Polycystic kidney disease 2-like 1 protein) (Polycystin-2 homolog) | DISRUPTION PHENOTYPE | Intestinal malrotation in 50% of animals, while other organs do not show major organ laterality defects. Intestinal malformations are associated with SHH pathway defects during early development (PubMed:24336288). Partial reduction of chorda tympani nerve response to sour stimuli, without affecting sweet, salty, bitter, and umami perception (PubMed:21625513). {ECO:0000269|PubMed:21625513, ECO:0000269|PubMed:24336288}. |