Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:329421
  • Symbol:Myo3b
  • Description:myosin IIIB
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Gene ID Entry Entry Name Protein Name Type Information
329421 Q1EG27 MYO3B_MOUSE Myosin-IIIb (EC 2.7.11.1) DISRUPTION PHENOTYPE MYO3B single knockout mice do not exhibit early hearing impairment whereas mice with a double knockout of MYO3A and MYO3B are profoundly deaf at 1 month of age. Cochlear hair bundles have abnormally long stereocilia and show dynamic shape defects during development. {ECO:0000269|PubMed:26754646}.