Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:329628
  • Symbol:Fat4
  • Description:FAT atypical cadherin 4
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Gene ID Entry Entry Name Protein Name Type Information
329628 Q2PZL6 FAT4_MOUSE Protocadherin Fat 4 (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J) DISRUPTION PHENOTYPE Deficient mice exhibit postnatal lethality, growth retardation, small lungs, abnormal cochlea morphology, abnormal kidney morphology, cardiovascular abnormalities and skeletal abnormalities. DCHS1 and FAT4 single mutants and DCHS1/FAT4 double mutants have similar phenotypes. {ECO:0000269|PubMed:18604206, ECO:0000269|PubMed:21303848, ECO:0000269|PubMed:24056717}.