| 384309 | Q80VI1 | TRI56_MOUSE | E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (Tripartite motif-containing protein 56) | DISRUPTION PHENOTYPE | High susceptibility to DNA virus infection, such as lethal herpes simplex virus-1 (HSV-1) (PubMed:29426904). Cells are defective in CGAS-mediated type I interferon IFN-beta production upon HSV-1 infection (PubMed:29426904). No susceptibility to RNA virus infection, such as influenza A virus (PubMed:29426904). No visible phenotype in normal conditions (PubMed:29426904). {ECO:0000269|PubMed:29426904}. |