| 50767 | Q3TRM4 | PLPL6_MOUSE | Patatin-like phospholipase domain-containing protein 6 (Neuropathy target esterase) (EC 3.1.1.5) | DISRUPTION PHENOTYPE | Embryonically lethal. At 9 dpc, embryos are smaller, and their development is delayed (PubMed:12640454). At 10-11 dpc, the development is arrested with signs of resorption (PubMed:12640454). Heterozygous mice have lower catalytic activity towards the synthetic compound phenyl valerate in the brain and show increased motor activity (PubMed:12640454). {ECO:0000269|PubMed:12640454}. |