| 50817 | Q9JLG8 | CAN15_MOUSE | Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog) | DISRUPTION PHENOTYPE | Knockout animals show significantly reduced viability. Homozygous knockout mice also weigh significantly less than their wild-type or heterozygous littermates. These mice also display severe developmental eye defects, including anophthalmia, microphthalmia, and cataract, and the presence of these phenotypes is significantly increased compared to wild-type or heterozygous mice. {ECO:0000269|PubMed:32885237}. |