Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:58231
  • Symbol:Stk4
  • Description:serine/threonine kinase 4
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Gene ID Entry Entry Name Protein Name Type Information
58231 Q9JI11 STK4_MOUSE Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)] DISRUPTION PHENOTYPE Mice show progressive hepatomegaly with a 2-fold increase in liver mass relative to total body mass at 1 month of age and a 3-fold increase by 3 months of age. {ECO:0000269|PubMed:20080689}.