| 620246 | P0C5J4 | GPR52_MOUSE | G-protein coupled receptor 52 | DISRUPTION PHENOTYPE | Gpr52 knockout mice are normal in body and brain weight. In the open field test, mice stay and move around the central zone significantly longer. The total distance traveled and brain morphology are normal. Mice are much more sensitive to the startle response following dizocilpine administration. Thus mice displayed psychosis-related behaviors (PubMed:24587241). Mice exhibit a significantly higher istradefylline-induced locomotor activity (PubMed:28583861). {ECO:0000269|PubMed:24587241, ECO:0000269|PubMed:28583861}. |