Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:65100
  • Symbol:Zic5
  • Description:zinc finger protein of the cerebellum 5
Export (tab separated) Export to Excel
Gene ID Entry Entry Name Protein Name Type Information
65100 Q7TQ40 ZIC5_MOUSE Zinc finger protein ZIC 5 (Odd paired-related protein) (Opa-related protein) (Zinc finger protein of the cerebellum 5) DISRUPTION PHENOTYPE Mice exhibited insufficient neural tube closure at the rostral end and malformation of neural-crest-derived facial bones especially the mandible. After birth, mice were significantly smaller than their littermates and most of them died within 2 months. {ECO:0000269|PubMed:15136147}.