Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:68497
  • Symbol:Arel1
  • Description:apoptosis resistant E3 ubiquitin protein ligase 1
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Gene ID Entry Entry Name Protein Name Type Information
68497 Q8CHG5 AREL1_MOUSE Apoptosis-resistant E3 ubiquitin protein ligase 1 (EC 2.3.2.26) (Apoptosis-resistant HECT-type E3 ubiquitin transferase 1) DISRUPTION PHENOTYPE Mice show significant and stepwise decreases in indicators of inflammatory injury, such as bronchoalveolar lavage fluid protein concentration and cell count, as well as decreases in pro-inflammatory cytokine release. {ECO:0000269|PubMed:31578312}.