Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:69675
  • Symbol:Pxdn
  • Description:peroxidasin
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Gene ID Entry Entry Name Protein Name Type Information
69675 Q3UQ28 PXDN_MOUSE Peroxidasin homolog (EC 1.11.2.-) [Cleaved into: PXDN active fragment] DISRUPTION PHENOTYPE Homozygous mice for the PXDN gene show completely or almost closed eyelids with small eyes, having no apparent external morphological defects in other organs (PubMed:31817535). In addition, mice show hair color change and the tail color is white and also have a white spot at the ventral and dorsal region at a frequency of about 94.1%. Some of mutants have severe cataracts in the eyes (PubMed:31817535). {ECO:0000269|PubMed:31817535}.