Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:70873
  • Symbol:Cnbd2
  • Description:cyclic nucleotide binding domain containing 2
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Gene ID Entry Entry Name Protein Name Type Information
70873 Q9D5U8 CNBD2_MOUSE Cyclic nucleotide-binding domain-containing protein 2 (Cyclic nucleotide receptor involved in sperm function) DISRUPTION PHENOTYPE Males are either infertile due to a lack of sperm resulting from spermatogenic arrest, or subfertile due to impaired sperm motility. The motility defect is caused by altered Ca(2+) regulation of the flagellar beat of sperm. {ECO:0000269|PubMed:24339785}.