Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:71389
  • Symbol:Chd6
  • Description:chromodomain helicase DNA binding protein 6
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Gene ID Entry Entry Name Protein Name Type Information
71389 A3KFM7 CHD6_MOUSE Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (EC 3.6.4.12) (ATP-dependent helicase CHD6) DISRUPTION PHENOTYPE Mice with targeted deletion of exon 12 lacking part of the Helicase ATP-binding domain are born in normal Mendelian ratios and are viable. They are fertile and exhibit no obvious morphological or histological difference. However, they display a coordination deficiency which is not due to muscle weakness or bradykinesia. {ECO:0000269|PubMed:20111866}.