Gene ID | Entry | Entry Name | Protein Name | Type | Information | 71602 | E9Q634 | MYO1E_MOUSE | Unconventional myosin-Ie (Unconventional myosin 1E) | DISRUPTION PHENOTYPE | No visible phenotype at birth. Mice exhibit massive proteinuria, combined with the presence of leukocytes and hemoglobin in the urine. They develop enlarged kidneys, present damage to the glomeruli, renal inflammation and fibrosis. In the glomeruli, the thickness of the basement membrane is increased, and podocytes fail to develop normal foot processes. {ECO:0000269|PubMed:19005011}. |
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