Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:71960
  • Symbol:Myh14
  • Description:myosin, heavy polypeptide 14
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Gene ID Entry Entry Name Protein Name Type Information
71960 Q6URW6 MYH14_MOUSE Myosin-14 (Myosin heavy chain 14) (Myosin heavy chain, non-muscle IIc) (Non-muscle myosin heavy chain IIc) (NMHC II-C) DISRUPTION PHENOTYPE Survival to adulthood with no obvious defects in brain structure, lung and heart development and no evidence for defective cell division. Deletion in animals expressing only 12% of wild-type amounts of Myh10 results in an increase in cardiac myocyte hypertrophy and interstitial fibrosis compared with the Myh10 hypomorphic animal. {ECO:0000269|PubMed:20861308}.