| 75605 | Q80Y84 | KDM5B_MOUSE | Lysine-specific demethylase 5B (EC 1.14.11.67) (Histone demethylase JARID1B) (Jumonji/ARID domain-containing protein 1B) (PLU-1) ([histone H3]-trimethyl-L-lysine(4) demethylase 5B) | DISRUPTION PHENOTYPE | Homozygous KDM5B-null mice are subviable, exhibit vertebral patterning defects, and manifest numerous behavioral abnormalities including increased anxiety, less sociability, and reduced long-term memory compared with that of wild-types. Heterozygous mice appear normal. {ECO:0000269|PubMed:30409806}. |