76365 | Q9EPZ6 | TBX18_MOUSE | T-box transcription factor TBX18 (T-box protein 18) | DISRUPTION PHENOTYPE | Deficient mice fail to maintain anterior-posterior polarity, resulting in abnormal dorsal-ventral polarity of the somites. Mutant mice display neonatal lethality and abnormal morphology of vertebrae, ribs, spinal nerves and coronary vessels. Besides, mutant mice develop anomalies of the urinary tract, including hydroureter and hydronephrosis. {ECO:0000269|PubMed:15155583, ECO:0000269|PubMed:16511601, ECO:0000269|PubMed:19096026, ECO:0000269|PubMed:24016759}. |