Mine Disruption Phenotype

Gene Info

  • Species:Mouse (Mus musculus)
  • GeneID:76843
  • Symbol:Dtl
  • Description:denticleless E3 ubiquitin protein ligase
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Gene ID Entry Entry Name Protein Name Type Information
76843 Q3TLR7 DTL_MOUSE Denticleless protein homolog (Lethal(2) denticleless protein homolog) (Meth A retinoic acid-regulated nuclear matrix-associated protein) (Meth A RAMP) (Retinoic acid-regulated nuclear matrix-associated protein) DISRUPTION PHENOTYPE Early embryonic lethality due to cell cycle progression failure, termination of cell division, and, eventually, embryonic death during the preimplantation stage. {ECO:0000269|PubMed:17107960}.