Gene ID | Entry | Entry Name | Protein Name | Type | Information | 83964 | Q9D8B7 | JAM3_MOUSE | Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)] | DISRUPTION PHENOTYPE | Important mortality during the postnatal period; about 40% of the mutant mice survive. Mutant males are infertile; they have strongly reduced testis size and fail to produce mature sperm cells. Developing spermatids fail to become polarized, and do not form acrosomes. {ECO:0000269|PubMed:15372036}. |
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