852233 | P34216 | EDE1_YEAST | EH domain-containing and endocytosis protein 1 (Bud site selection protein 15) | DISRUPTION PHENOTYPE | Random budding pattern and morphological defects. Defects in fluid-phase endocytosis and defective internalization of the pheromone alpha-factor and uracil permease. Deletion has only a small impact on actin cytoskeleton organization. Deletion shows synthetic growth defects with thermosensitive mutants of PAN1, END3 and RSP5. {ECO:0000269|PubMed:10954428, ECO:0000269|PubMed:11452010}. |