| 853186 | P40340 | ATAD2_YEAST | ATPase histone chaperone YTA7 (EC 3.6.1.-) (ATPase family AAA domain-containing protein YTA7) (AAA-ATPase) (Tat-binding homolog 7) | DISRUPTION PHENOTYPE | Decreases the level of CSE4/CENP-A at centromeres (PubMed:32079723). Decreases internucleosome spacing at protein-coding genes (PubMed:25406467). Decreases localization of RNA polymerase II to the histone HTA1-HTB1 gene locus during the G1/S transition (PubMed:22156209). Decreases HTA1 RNA level (PubMed:19683497). Heterochromatin spreading downstream of the silent mating-type locus HMR (PubMed:16079223). Decreases cell population growth; simultaneous disruption of proteins required for maintaining centromere and kinetochore function, including CLH4 and CBF1, enhances the growth defect (PubMed:32079723). {ECO:0000269|PubMed:16079223, ECO:0000269|PubMed:19683497, ECO:0000269|PubMed:22156209, ECO:0000269|PubMed:25406467, ECO:0000269|PubMed:32079723}. |