Mine Disruption Phenotype

Gene Info

  • Species:Yeast (Saccharomyces cerevisiae)
  • GeneID:854149
  • Symbol:HRD1
  • Description:E3 ubiquitin-protein ligase HRD1
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Gene ID Entry Entry Name Protein Name Type Information
854149 Q08109 HRD1_YEAST ERAD-associated E3 ubiquitin-protein ligase HRD1 (EC 2.3.2.27) (HMG-CoA reductase degradation protein 1) (RING-type E3 ubiquitin transferase HRD1) DISRUPTION PHENOTYPE Impaired degradation of proteins with misfolded intramembrane or lumenal domains. {ECO:0000269|PubMed:16873066, ECO:0000269|PubMed:20005842}.