Mine Disruption Phenotype

Gene Info

  • Species:Yeast (Saccharomyces cerevisiae)
  • GeneID:855613
  • Symbol:NOP15
  • Description:rRNA-binding ribosome biosynthesis protein NOP15
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Gene ID Entry Entry Name Protein Name Type Information
855613 P53927 NOP15_YEAST Ribosome biogenesis protein 15 (Nucleolar protein 15) DISRUPTION PHENOTYPE Essential gene. Abrupt growth arrest prior to substantial depletion of ribosomal subunits. Fails to synthesize the 25S and 5.8S rRNA components of the 60S ribosomal subunit, and exonucleolytic 5' processing of 5.8S rRNA is strongly inhibited. Arrests at cytokinesis and fails to assemble a contractile actin ring at the bud neck. {ECO:0000269|PubMed:10953080, ECO:0000269|PubMed:14657029}.