| 171838 | Q9N2L7 | PLK2_CAEEL | Serine/threonine-protein kinase plk-2 (EC 2.7.11.21) (Polo-like kinase 2) | DISRUPTION PHENOTYPE | Mutants are viable and fertile but about 30-percent of the progeny die at the embryonic stage. Surviving adults are mostly male (PubMed:22018922). Impaired chromosome pairing and synapsis during meiotic prophase. Asymmetric disassembly of the synaptonemal complex fails at the diplotene stage. Partial mis-segregation of chromosomes. Increased germline apoptosis (PubMed:22018922). Simultaneous knockdown of plk-1 and plk-2 causes a loss in pie-1 polarization in the 1-cell embryo, an increased association with the oocyte pronuclei and a decrease in pie-1 degradation in embryonic somatic cells (PubMed:18199581). {ECO:0000269|PubMed:18199581, ECO:0000269|PubMed:22018922}. |