Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:171872
  • Symbol:mek-2
  • Description:Dual specificity mitogen-activated protein kinase kinase mek-2
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Gene ID Entry Entry Name Protein Name Type Information
171872 Q10664 MEK2_CAEEL Dual specificity mitogen-activated protein kinase kinase mek-2 (MAP kinase kinase mek-2) (EC 2.7.12.2) DISRUPTION PHENOTYPE RNAi-mediated knockdown causes a defect in pachytene progression resulting in a proximal gonad devoid of nuclei. The phenotype is more severe in gck-1 km15 mutant background (PubMed:19826475). RNAi-mediated knockdown in adults decreases lifespan (PubMed:20624915). {ECO:0000269|PubMed:19826475, ECO:0000269|PubMed:20624915}.