Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:172059
  • Symbol:ceh-17
  • Description:Homeobox domain-containing protein
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Gene ID Entry Entry Name Protein Name Type Information
172059 G5EC89 CEH17_CAEEL Homeobox protein ceh-17 DISRUPTION PHENOTYPE ALA and SIA axons exhibit outgrowth abnormalities, failing to run along the lateral cord to the tail (PubMed:10887091). ALA axons are shortened further in a vab-8 mutant background (PubMed:10887091). Drastically reduced expression of let-23/EGFR and plc-3/PLCgamma in ALA neurons (PubMed:20501595). RNAi-mediated knockdown causes severe defects in the ALA neuron in young adults (PubMed:20501595). {ECO:0000269|PubMed:10887091, ECO:0000269|PubMed:20501595}.