Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:172088
  • Symbol:let-502
  • Description:Rho-associated protein kinase let-502
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Gene ID Entry Entry Name Protein Name Type Information
172088 P92199 ROCK_CAEEL Rho-associated protein kinase let-502 (EC 2.7.11.1) (Lethal protein 502) (Rho-binding kinase let-502) DISRUPTION PHENOTYPE Loss of both zygotic and maternal expression causes defects in embryonic elongation and P-cell migration, loss of only maternal expression results in abnormal early cleavages, loss of only zygotic expression results in sterility. {ECO:0000269|PubMed:11102366, ECO:0000269|PubMed:11687661, ECO:0000269|PubMed:12006612, ECO:0000269|PubMed:17537791, ECO:0000269|PubMed:9042856}.