Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:172268
  • Symbol:air-2
  • Description:Aurora/IPL1-related protein kinase 2
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Gene ID Entry Entry Name Protein Name Type Information
172268 O01427 AIR2_CAEEL Aurora/IPL1-related protein kinase 2 (EC 2.7.11.1) (Serine/threonine-protein kinase aurora-B) DISRUPTION PHENOTYPE RNAi-mediated knockdown disrupts the localization of the condensin subunit smc-4 to mitotic chromosomes (PubMed:11914278). RNAi-mediated knockdown causes failure in mitotic chromosome segregation and cytokinesis, leading to aneuploidy (PubMed:11914278, PubMed:12213836). {ECO:0000269|PubMed:11914278, ECO:0000269|PubMed:12213836}.