Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:172612
  • Symbol:mei-1
  • Description:Meiotic spindle formation protein mei-1
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Gene ID Entry Entry Name Protein Name Type Information
172612 P34808 KTNA1_CAEEL Meiotic spindle formation protein mei-1 (EC 5.6.1.1) (Katanin p60 ATPase-containing subunit A1) (Katanin p60 subunit A1) (p60 katanin) DISRUPTION PHENOTYPE RNAi-mediated knockdown at the L1 larval stage results in the disorganization of myosin thick filaments in adult body wall muscles characterized by the formation of abnormal myosin heavy chain myo-3 aggregates and V-shaped crossing of A-bands. In addition, body wall muscle cells appear shorter and broader. {ECO:0000269|PubMed:22621901}.