172628 | A5JYW9 | SIN3_CAEEL | Paired amphipathic helix protein sin-3 (Histone deacetylase complex subunit sin-3) (Transcriptional corepressor sin-3) | DISRUPTION PHENOTYPE | Uncoordinated movement, protruding vulva and ray fusion defects in the male tail (PubMed:17506990). RNAi-mediated knockdown results in sterility (PubMed:16710447). RNAi-mediated knockdown in a him-8 mutant background results in no deposition of dimethylated 'Lys-9' of histone H3 (H3K9me2) on asynapsed chromosome pairs (PubMed:21909284). {ECO:0000269|PubMed:16710447, ECO:0000269|PubMed:17506990, ECO:0000269|PubMed:21909284}. |