Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:172910
  • Symbol:ned-8
  • Description:NEDD8
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Gene ID Entry Entry Name Protein Name Type Information
172910 Q93725 NEDD8_CAEEL NEDD8 (Neddylin) (Protein NED-8) (Ubiquitin-like protein Nedd8) DISRUPTION PHENOTYPE Worms either arrest during embryonic development, or show vulval eversion at the L4 stage and burst at the vulva during the L4-to-adult molt. Those who survive to the adult stage display severe defects in terminal differentiation of seam cells, vulva and male tail. {ECO:0000269|PubMed:10993680}.