Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:173149
  • Symbol:gsk-3
  • Description:Glycogen synthase kinase-3
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Gene ID Entry Entry Name Protein Name Type Information
173149 Q9U2Q9 GSK3_CAEEL Glycogen synthase kinase-3 (EC 2.7.11.26) DISRUPTION PHENOTYPE Worms exhibit defects in endoderm specification and mitotic spindle alignment (PubMed:10444600). RNAi-mediated knockdown results in stability and delayed degradation of the maternal oocyte protein oma-1 in embryos beyond the 2-cell stage (PubMed:16289132). {ECO:0000269|PubMed:10444600, ECO:0000269|PubMed:16289132}.