| 173801 | Q09EF7 | CROCC_CAEEL | Rootletin (Abnormal dye filling protein 14) (Chemotaxis abnormal protein 10) | DISRUPTION PHENOTYPE | Ciliary degeneration which is partly due to irregular localization of ciliary components (PubMed:24094853). This likely leads to the impaired intraflagellar transport of proteins along the ciliary axoneme during the later stages of larval development (PubMed:24094853). Lack of or defects in amphid cilia including no transition zone and axoneme structures in amphid wing neurons, enlargened dendritic endings, variable cilia length of ADL neurons, absent or irregularly orientated cilia of the AFD neuron and absent striated rootlets which are normally associated with cilia basal bodies and positioned at the base of cilia in IL1, OLQ and BAG neurons (PubMed:2428682, PubMed:17314406, PubMed:24094853). Behavioral defects including no obvious mating behavior, impaired dauer formation, osmotic and CO(2+) avoidance and impaired chemotaxis (PubMed:2428682, PubMed:24094853). {ECO:0000269|PubMed:17314406, ECO:0000269|PubMed:24094853, ECO:0000269|PubMed:2428682}. |