| 174121 | Q09228 | EGL27_CAEEL | Egg-laying defective protein 27 | DISRUPTION PHENOTYPE | Shortened lifespan and reduced survival in response to heat stress. Impaired differentiation of the Y rectal cell to the PDA neuron with the Y cell remaining undifferentiated in its original rectal location. Double RNAi-mediated knockdown with lin-40 results in delayed cell cycle progression in mesodermal and endodermal embryonic lineages, but accelerated cell cycle progression in a subset of embryonic lineages (PubMed:25446273). {ECO:0000269|PubMed:22493276, ECO:0000269|PubMed:23271974, ECO:0000269|PubMed:25446273}. |