Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:174460
  • Symbol:pir-1
  • Description:RNA/RNP complex-1-interacting phosphatase homolog
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Gene ID Entry Entry Name Protein Name Type Information
174460 Q22707 DUS11_CAEEL RNA/RNP complex-1-interacting phosphatase homolog (EC 3.1.3.-) (Dual specificity protein phosphatase 11 homolog) (Phosphatase interacting with RNA/RNP complex-1) DISRUPTION PHENOTYPE Arrests at the L4 larval stage due to a failure to undergo the L4 to adult molt. Sterile due to the lack of functional gametes. In RNAi-mediated knockdown assays, fails to process dsRNA which results in the accumulation of high molecular weight dsRNA-derived RNA species. {ECO:0000269|PubMed:16439208}.