Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:174830
  • Symbol:lin-29
  • Description:Uncharacterized protein
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Gene ID Entry Entry Name Protein Name Type Information
174830 G5EGB2 LIN29_CAEEL Zinc finger transcription factor lin-29 (abnormal cell lineage 29) DISRUPTION PHENOTYPE RNAi-mediated knockdown abolished expression of collagen col-38 at mid-to-late larval stage L4 (PubMed:29604168). Knockdown, whether untargeted, or hypodermis-specific, represses intestinal genes involved in fatty acid metabolism and beta-oxidation in the L4 larval stage (PubMed:31974205). Drastically reduces expression of the vitellogenin genes (PubMed:27401555). Knockdown causes transcription factor pqm-1 to accumulate in the intestinal nuclei at adulthood, but has no effect on daf-16 localization (PubMed:27401555). {ECO:0000269|PubMed:27401555, ECO:0000269|PubMed:29604168, ECO:0000269|PubMed:31974205}.