Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:174974
  • Symbol:mac-1
  • Description:Protein mac-1
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Gene ID Entry Entry Name Protein Name Type Information
174974 Q9NAG4 MAC1_CAEEL Protein mac-1 (Member of AAA family that binds ced-4) DISRUPTION PHENOTYPE RNAi-mediated knockdown causes an arrest at the L2-L3 larval stages with few adults reaching adulthood. Abnormal presence of vacuoles in the intestine with some intestinal sections almost completely degraded. RNAi-mediated knockdown in a ced-3 (n718) or ced-4 (n1416) mutant background causes a similar arrest at the L2-L3 larval stages. {ECO:0000269|PubMed:10101135}.