| 175223 | Q09639 | GRK2_CAEEL | G protein-coupled receptor kinase 2 (EC 2.7.11.16) | DISRUPTION PHENOTYPE | Defective egg-laying with mutants retaining 35 eggs compared to 13-14 eggs in wild-type worms (PubMed:28213524, PubMed:28968387). Reduced serotonin levels, increased levels of the serotonin metabolite 5-hydroxyindoleacetic acid, increased levels of amine oxidase amx-2 in early adult stages and reduced levels of phosphorylated amx-2 (PubMed:28213524). Defective locomotion and reduced body length (PubMed:28968387). {ECO:0000269|PubMed:28213524, ECO:0000269|PubMed:28968387}. |