Mine Disruption Phenotype

Gene Info

  • Species:Worm (Caenorhabditis elegans)
  • GeneID:175502
  • Symbol:tir-1
  • Description:ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein tir-1
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Gene ID Entry Entry Name Protein Name Type Information
175502 Q86DA5 SARM1_CAEEL NAD(+) hydrolase tir-1 (NADase tir-1) (EC 3.2.2.6) (Neuronal symmetry protein 2) (SARM1 homolog) (Sterile alpha and TIR motif-containing protein tir-1) DISRUPTION PHENOTYPE RNAi-mediated knockdown results in reduced survival and reduced pmk-1 phosphorylation in response to the heavy metal arsenite. {ECO:0000269|PubMed:25204677}.